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Key Takeaways:

  • Batch systems suit small-scale use; continuous systems maximize throughput and space.
  • System design must match BSL levels, with higher tiers requiring monitoring and containment.
  • Continuous systems run hotter (150–165°C) for 3–10 sec, cutting utility use and boosting efficiency.
  • Solid-laden waste requires pre-treatment to prevent process issues and excessive maintenance.
  • Equipment must use Geobacillus stearothermophilus BIs and be built to avoid leaks and cross-contamination. 

STERIS Life Sciences’ Juha Mattila, Senior Product Engineer for STERIS Life Sciences’ Engineered Products wrote a fascinating article on Engineering and Design Considerations for Thermal Inactivation of Bio-Hazardous Waste Streams which was published in Pharmaceutical Engineering, November/December 2011 Vol. 31 no 6.

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